Methylation Activation

$59.97

Experience the New Methylation Activation – Now in Capsule Form!

Discover a new level of whole-body wellness with our advanced Methylation Activation formula, now available in convenient capsule form. This cutting-edge supplement continues to deliver unparalleled support for over 250 essential biochemical reactions in the body.

Why Methylation Activation?

Our unique formula is crafted with highly bioavailable ingredients, including Methyl Folate (L-5-MTHF), Methylcobalamin, Pyridoxal 5 Phosphate (B6), and Trimethylglycine (TMG), to optimize methylation processes. These processes are critical in DNA synthesis, neurotransmitter balance, and cellular energy production, promoting enhanced cognitive function, cardiovascular health, and optimal detoxification.

Key Benefits Include:

  • Optimal DNA Synthesis and Cellular Repair: Delivering crucial methyl donors to support healthy cell function.

  • Mood, Focus & Brain Health Support: Regulates neurotransmitter production, providing mental clarity and stability.

  • Homocysteine Balance & Heart Health: Converts homocysteine into beneficial compounds, reducing cardiovascular risk.

  • Detoxification & Antioxidant Protection: Strengthens the body’s natural detox pathways to combat oxidative stress.

  • Enhanced Energy Metabolism: Optimizes cellular energy production with a potent B vitamins and antioxidants blend.

Your Genes, Folate, and Human Health 

Folate is an essential nutrient needed during rapid cell division and growth. It is no surprise that the need for dietary folates doubles during pregnancy. 

Folate coenzymes play a vital role in metabolism through two different pathways: the synthesis of DNA from its precursors (purines/thymidines) and the homocysteine (methionine) pathway. 

5-MTHF is needed for the conversion of homocysteine to methionine, which allows for the production of S-adenosylmethionine (known as SAMe). This is important because SAMe is the universal methyl donor. Methyl-group donation is vital to proper cell replication and differentiation and to hundreds of biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.

MTHFR And The Other Methylation Genes

A mutation in the MTHFR gene impacts how well the MTHFR enzyme performs. An MTHFR deficiency may lead to hyperhomocysteinemia. Several MTHFR gene mutations result in a mild to severe impairment of the activity of the MTHFR enzyme, the most characterized mutation being C677T (C677T MTHFR mutation). 

This gene mutation makes a person more susceptible to: 

  • Anxiety

  • Depression

  • Neurodegenerative diseases and conditions

  • Coronary heart disease

  • Stroke

  • Preeclampsia (high blood pressure in pregnant women)

  • Birth defects including neural tube defects 

Research studies have also correlated this with brain and spinal cord demyelination. 

L-5-MTHF should be considered when high doses of folate are needed for Individuals who have tested homozygous with either the A1298C or C677T MTHFR mutation or those with elevated homocysteine levels. BioOne Sciences Methylation Activation, in the form of L-5-MTHF, is the preferred form of folate supplementation.

Recommended Use: Take two (2) capsules once per day with or without meals.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Experience the New Methylation Activation – Now in Capsule Form!

Discover a new level of whole-body wellness with our advanced Methylation Activation formula, now available in convenient capsule form. This cutting-edge supplement continues to deliver unparalleled support for over 250 essential biochemical reactions in the body.

Why Methylation Activation?

Our unique formula is crafted with highly bioavailable ingredients, including Methyl Folate (L-5-MTHF), Methylcobalamin, Pyridoxal 5 Phosphate (B6), and Trimethylglycine (TMG), to optimize methylation processes. These processes are critical in DNA synthesis, neurotransmitter balance, and cellular energy production, promoting enhanced cognitive function, cardiovascular health, and optimal detoxification.

Key Benefits Include:

  • Optimal DNA Synthesis and Cellular Repair: Delivering crucial methyl donors to support healthy cell function.

  • Mood, Focus & Brain Health Support: Regulates neurotransmitter production, providing mental clarity and stability.

  • Homocysteine Balance & Heart Health: Converts homocysteine into beneficial compounds, reducing cardiovascular risk.

  • Detoxification & Antioxidant Protection: Strengthens the body’s natural detox pathways to combat oxidative stress.

  • Enhanced Energy Metabolism: Optimizes cellular energy production with a potent B vitamins and antioxidants blend.

Your Genes, Folate, and Human Health 

Folate is an essential nutrient needed during rapid cell division and growth. It is no surprise that the need for dietary folates doubles during pregnancy. 

Folate coenzymes play a vital role in metabolism through two different pathways: the synthesis of DNA from its precursors (purines/thymidines) and the homocysteine (methionine) pathway. 

5-MTHF is needed for the conversion of homocysteine to methionine, which allows for the production of S-adenosylmethionine (known as SAMe). This is important because SAMe is the universal methyl donor. Methyl-group donation is vital to proper cell replication and differentiation and to hundreds of biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.

MTHFR And The Other Methylation Genes

A mutation in the MTHFR gene impacts how well the MTHFR enzyme performs. An MTHFR deficiency may lead to hyperhomocysteinemia. Several MTHFR gene mutations result in a mild to severe impairment of the activity of the MTHFR enzyme, the most characterized mutation being C677T (C677T MTHFR mutation). 

This gene mutation makes a person more susceptible to: 

  • Anxiety

  • Depression

  • Neurodegenerative diseases and conditions

  • Coronary heart disease

  • Stroke

  • Preeclampsia (high blood pressure in pregnant women)

  • Birth defects including neural tube defects 

Research studies have also correlated this with brain and spinal cord demyelination. 

L-5-MTHF should be considered when high doses of folate are needed for Individuals who have tested homozygous with either the A1298C or C677T MTHFR mutation or those with elevated homocysteine levels. BioOne Sciences Methylation Activation, in the form of L-5-MTHF, is the preferred form of folate supplementation.

Recommended Use: Take two (2) capsules once per day with or without meals.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Experience the New Methylation Activation – Now in Capsule Form!

Discover a new level of whole-body wellness with our advanced Methylation Activation formula, now available in convenient capsule form. This cutting-edge supplement continues to deliver unparalleled support for over 250 essential biochemical reactions in the body.

Why Methylation Activation?

Our unique formula is crafted with highly bioavailable ingredients, including Methyl Folate (L-5-MTHF), Methylcobalamin, Pyridoxal 5 Phosphate (B6), and Trimethylglycine (TMG), to optimize methylation processes. These processes are critical in DNA synthesis, neurotransmitter balance, and cellular energy production, promoting enhanced cognitive function, cardiovascular health, and optimal detoxification.

Key Benefits Include:

  • Optimal DNA Synthesis and Cellular Repair: Delivering crucial methyl donors to support healthy cell function.

  • Mood, Focus & Brain Health Support: Regulates neurotransmitter production, providing mental clarity and stability.

  • Homocysteine Balance & Heart Health: Converts homocysteine into beneficial compounds, reducing cardiovascular risk.

  • Detoxification & Antioxidant Protection: Strengthens the body’s natural detox pathways to combat oxidative stress.

  • Enhanced Energy Metabolism: Optimizes cellular energy production with a potent B vitamins and antioxidants blend.

Your Genes, Folate, and Human Health 

Folate is an essential nutrient needed during rapid cell division and growth. It is no surprise that the need for dietary folates doubles during pregnancy. 

Folate coenzymes play a vital role in metabolism through two different pathways: the synthesis of DNA from its precursors (purines/thymidines) and the homocysteine (methionine) pathway. 

5-MTHF is needed for the conversion of homocysteine to methionine, which allows for the production of S-adenosylmethionine (known as SAMe). This is important because SAMe is the universal methyl donor. Methyl-group donation is vital to proper cell replication and differentiation and to hundreds of biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.

MTHFR And The Other Methylation Genes

A mutation in the MTHFR gene impacts how well the MTHFR enzyme performs. An MTHFR deficiency may lead to hyperhomocysteinemia. Several MTHFR gene mutations result in a mild to severe impairment of the activity of the MTHFR enzyme, the most characterized mutation being C677T (C677T MTHFR mutation). 

This gene mutation makes a person more susceptible to: 

  • Anxiety

  • Depression

  • Neurodegenerative diseases and conditions

  • Coronary heart disease

  • Stroke

  • Preeclampsia (high blood pressure in pregnant women)

  • Birth defects including neural tube defects 

Research studies have also correlated this with brain and spinal cord demyelination. 

L-5-MTHF should be considered when high doses of folate are needed for Individuals who have tested homozygous with either the A1298C or C677T MTHFR mutation or those with elevated homocysteine levels. BioOne Sciences Methylation Activation, in the form of L-5-MTHF, is the preferred form of folate supplementation.

Recommended Use: Take two (2) capsules once per day with or without meals.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.